diff --git a/aeron-driver/src/main/c/CMakeLists.txt b/aeron-driver/src/main/c/CMakeLists.txt
index 1234567..abcdefg 100644
--- a/aeron-driver/src/main/c/CMakeLists.txt
+++ b/aeron-driver/src/main/c/CMakeLists.txt
@@ -36,15 +36,39 @@ if (NOT MSVC)
 endif ()

 check_include_file("bsd/stdlib.h" BSDSTDLIB_H_EXISTS)
-check_include_file("uuid/uuid.h" UUID_H_EXISTS)
 find_library(LIBBSD_EXISTS NAMES bsd libbsd)
-find_library(LIBUUID_EXISTS NAMES uuid libuuid libuuid.dll)
+find_library(LIBUUID_SYSTEM NAMES uuid libuuid libuuid.dll)
+
+# In vcpkg builds on Linux, use vcpkg's libuuid
+if(DEFINED VCPKG_TOOLCHAIN AND CMAKE_SYSTEM_NAME MATCHES "Linux")
+    find_package(unofficial-libuuid QUIET CONFIG)
+    if(TARGET unofficial::UUID::uuid)
+        get_target_property(UUID_INCLUDE_DIR unofficial::UUID::uuid INTERFACE_INCLUDE_DIRECTORIES)
+        if(UUID_INCLUDE_DIR)
+            list(APPEND CMAKE_REQUIRED_INCLUDES "${UUID_INCLUDE_DIR}")
+        endif()
+        list(APPEND CMAKE_REQUIRED_LIBRARIES "unofficial::UUID::uuid")
+        set(LIBUUID_EXISTS TRUE)
+        set(AERON_LIB_UUID_LIBS "unofficial::UUID::uuid")
+        set(UUID_H_EXISTS TRUE)
+        set(UUID_GENERATE_PROTOTYPE_EXISTS TRUE)
+    endif()
+endif()
+
+if(NOT DEFINED LIBUUID_EXISTS OR NOT LIBUUID_EXISTS)
+    set(LIBUUID_EXISTS ${LIBUUID_SYSTEM})
+endif()
+
+# Only check for uuid headers if not found via vcpkg
+if(NOT DEFINED UUID_H_EXISTS OR NOT UUID_H_EXISTS)
+    check_include_file("uuid/uuid.h" UUID_H_EXISTS)
+endif()

 if (LIBBSD_EXISTS)
     set(CMAKE_REQUIRED_LIBRARIES "${CMAKE_REQUIRED_LIBRARIES} -lbsd")
 endif ()

-if (LIBUUID_EXISTS)
+if (LIBUUID_EXISTS AND NOT AERON_LIB_UUID_LIBS)
     set(CMAKE_REQUIRED_LIBRARIES "${CMAKE_REQUIRED_LIBRARIES} -luuid")
 endif ()

@@ -64,7 +88,9 @@ if (MSVC AND "${CMAKE_SYSTEM_NAME}" MATCHES "Windows")
     set(WSAPOLL_PROTOTYPE_EXISTS True)
 endif ()

-check_symbol_exists(uuid_generate "uuid/uuid.h" UUID_GENERATE_PROTOTYPE_EXISTS)
+if(NOT DEFINED UUID_GENERATE_PROTOTYPE_EXISTS OR NOT UUID_GENERATE_PROTOTYPE_EXISTS)
+    check_symbol_exists(uuid_generate "uuid/uuid.h" UUID_GENERATE_PROTOTYPE_EXISTS)
+endif()

 check_symbol_exists(poll "poll.h" POLL_PROTOTYPE_EXISTS)
 check_symbol_exists(epoll_create "sys/epoll.h" EPOLL_PROTOTYPE_EXISTS)
@@ -387,7 +413,7 @@ if ("${CMAKE_SYSTEM_NAME}" MATCHES "Linux")
         set(AERON_LIB_BSD_LIBS bsd)
     endif ()

-    if (LIBUUID_EXISTS)
+    if (LIBUUID_EXISTS AND NOT AERON_LIB_UUID_LIBS)
         set(AERON_LIB_UUID_LIBS uuid)
     endif ()

@@ -400,7 +426,7 @@ if ("${CMAKE_SYSTEM_NAME}" MATCHES "Linux")
 endif ()

 if (CYGWIN)
-    if (LIBUUID_EXISTS)
+    if (LIBUUID_EXISTS AND NOT AERON_LIB_UUID_LIBS)
         set(AERON_LIB_UUID_LIBS uuid)
     endif ()
 endif ()